ウイルス感染による、核と細胞質間でのタンパク質移行の変化をTimerタンパク質を用いて観察した例
Nucleocytoplasmic Traffic Disorder Induced by Cardioviruses
Peter V. Lidsky, Stanleyson Hato, Maryana V. Bardina, Alexei G. Aminev, Ann C. Palmenberg, Eugene V. Sheval, Vladimir Y. Polyakov, Frank J. M. van Kuppeveld, and Vadim I. Agol J. Virol. (2006) Mar;80:2705-2717.
膵臓分泌細胞の分化に関与するNeurogenin 3の発現をTimerタンパク質をレポーターにマウスで観察した例
Chronology of Islet Differentiation Revealed By Temporal Cell Labeling
Takeshi Miyatsuka, Zhongmei Li, and Michael S. German Diabetes (2009) Aug;58:1863-1868.
参考文献
Terskhik, A. et al. (2000) Science290(5496):1585-1588.
Living Colors Fluorescent Timer (April 2001) ClontechniquesXVI(2):14-15.