ケモカインレセプターCXCR4をHuman Ovary QUICK-Clone cDNAよりクローニングし、酵母Two-Hybrid法でsingle chain Fv antibodies (scFv)スクリーニングに進んだ例
CXCR4 and CXCL12 (SDF-1) in Prostate Cancer: Inhibitory Effects of Human Single Chain Fv Antibodies
Gayle G. Vaday, Shao-Bing Hua, Donna M. Peehl, Michelle H. Pauling, Yu-Huei Lin, Li Zhu, Diana M. Lawrence, Hussein D. Foda, and Stanley Zucker Clin. Cancer Res. (2004) Aug;10:5630-5639.
参考文献
Parmentier, M. et al. (1989) Science246:1620-1622.
Wilks, A. E. et al. (1989) Gene85:67-74.
Vallins, W. J. et al. (1990) FEBS Letters270:57-61.