シグナル伝達経路プロファイリングシステム
使用文献
- Pathway Profiling Luciferase Systemを用いてGSK-3の転写活性への影響を調べた例
Differential Roles of Glycogen Synthase Kinase-3 Isoforms in the Regulation of Transcriptional Activation
Min-Huei Liang and De-Maw Chuang
J. Biol. Chem. (2006) Oct;281:30479-30484. - pCMV-MEK1 Vectorを細胞に一過性に導入し、ERK1/2の活性を調べた例
Raf/MEK/ERK signalling triggers reactivation of Kaposi's sarcoma-associated herpesvirus latency
Patrick W. Ford, Benjaman A. Bryan, Ossie F. Dyson, Douglas A. Weidner, Vishnu Chintalgattu, and Shaw M. Akula
J. Gen. Virol. (2006) May;87:1139-1144. - pCMV-PKA Vectorを用いて、CREBやSF-1により転写調節を受けると考えられるチトクロームP4501B1の発現を調べた例
Binding of Steroidogenic Factor-1 to the Regulatory Region Might Not Be Critical for Transcriptional Regulation of the Human CYP1B1 Gene
Yuki Tsuchiya, Miki Nakajima, Shingo Takagi, Miki Katoh, Wenchao Zheng, Colin R Jefcoate, and Tsuyoshi Yokoi
J. Biochem. (2006) Mar;139:527-534. - Pathway Profiling SEAP Systemを用いてNF-kB転写経路の活性化を調べた例
LIGHT, a Member of the Tumor Necrosis Factor Ligand Superfamily, Prevents Tumor Necrosis Factor--mediated Human Primary Hepatocyte Apoptosis, but Not Fas-mediated Apoptosis
Hideki Matsui, Yukiko Hikichi, Isamu Tsuji, Takao Yamada, and Yasushi Shintani
J. Biol. Chem. (2002) Dec;277:50054-50061.
参考文献
- Ready-To-Glow Dual Secreted Reporter System (October 2006) Clontechniques XXI(3):1.
