文献

ProteoTuner™ Shield システム

使用文献

ALS関連変異タンパク質の研究
  • Watanabe, S., et al (2013) .Accelerated Disease Onset with Stabilized Familial Amyotrophic Lateral Sclerosis (ALS)-linked Mutant TDP-43 Proteins J. Biol. Chem.288:3641-3654.

イオンチャンネルの成り立ちと機能をモニタリング
  • Schoeber, J. P. H. et al. (2009) Am. J. Physiol. Renal Physiol. 296, F204-211.

Znフィンガー型ヌクレアーゼによる遺伝子修復を制御
  • Pruett-Miller, S. M. et al. (2009) PLoS Genetics 5(2):e1000376.

マウスにおける腫瘍形成の特徴
  • Banaszynski, L. A. et al. (2008) Nat. Med. 14(10):1123-1127.

寄生虫原虫における重要な遺伝子機能の解析例
  • Agop-Neresian, C. et al. (2009) PLoS Pathogens 5(1):e1000270.
  • Armstrong, C. M. and Goldberg, D. E. (2007) Nat. Meth. 4(12):1007-1009.
  • Herm-Götz, A. et al. (2007) Nat. Meth. 4(12):1003-1005. Erratum in: Nat. Meth. (2008) 5(1):113.

細胞骨格の再構築機構の解析例
  • On-Demand Protein Stabilization Using the Lenti-X ProteoTuner Systems (October 2008) Clontechniques XXIII(3):2-3.

線虫での細胞系譜の解析にDDを蛍光タンパク質不安定化タグとして利用
  • Shibata Y, et al.Double bromodomain protein BET-1 and MYST HATs establish and maintain stable cell fates in C. elegans.
    Development. 2010 Apr;137(7):1045-1053.

マイクロチューブ解析
  • Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.
    Tanaka, N. et al. (2012) Proc. Natl. Acad. Sci. USA, 109:20029-20034.

ProteoTuner Shield Systems Citation List

参考文献

  1. Laura A Banaszynski, et al. Chemical control of protein stability and function in living mice.
    Nat. Med. 2008 Oct;14(10):1123-1127.
  2. Armstrong CM, et al. An FKBP destabilization domain modulates protein levels in Plasmodium falciparum.
    Nat. Methods. 2007 Dec;4(12):1007-1009.
  3. Herm-GÖtz A, et al. Rapid control of protein level in the apicomplexan Toxoplasma gondii.
    Nat. Methods. 2007 Dec;4(12):1003-1005.
    Erratum in:Nat Methods. 2008 Jan;5(1):113.
  4. Maynard-Smith LA, et al. A directed approach for engineering conditional protein stability using biologically silent small molecules.
    J. Biol. Chem. 2007 Aug 24;282(34):24866-24872.
  5. Berdeaux R, et al. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes.
    Nat. Med. 2007 May;13(5):597-603.
  6. Banaszynski LA, et al. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules.
    Cell. 2006 Sep 8;126(5):995-1004.
  7. Banaszynski LA, et al. Conditional control of protein function.
    Chem. Biol. 2006 Jan;13(1):11-21. Review.