pLVX-Puro Vector (Lenti-X Expression System) にSurvivin遺伝子をクローニングし、Lenti-X HT Packaging Mixを用いてウイルスを調製した例
Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML
Jianbiao Zhou, Chonglei Bi, Jasinghe V. Janakakumara, Shaw-Cheng Liu, Wee-Joo Chng, Kian-Ghee Tay, Lai-Fong Poon, Zhigang Xie, Senthilnathan Palaniyandi, Hanry Yu, Keith B. Glaser, Daniel H. Albert, Steven K. Davidsen, and Chien-Shing Chen Blood, (2009) Apr;113:4052-4062.
参考文献
Zufferey, R. et al. (1999) J. Virol.73(4):2886-2892.