Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.
Muguruma K., et al. (2015) Cell Reports. 10:537-550.
Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells.
Muguruma K., et al. Nat Neurosci. 2010 Oct;13(10):1171-1180. doi: 10.1038/nn.2638.
Generation of cerebellar neuron precursors from embryonic stem cells.
Su HL., et al Dev Biol. 2006 Feb 15;290(2):287-296.
Otp
Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.
Wataya T., et al Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11796-11801. doi: 10.1073/pnas.0803078105.
Identification, chromosomal assignment, and expression analysis of the human homeodomain-containing gene Orthopedia (OTP).
Lin X., et al Genomics. 1999 Aug 15;60(1):96-104.
Emx1
Directed differentiation of telencephalic precursors from embryonic stem cells.
Watanabe K., et al Nat Neurosci. 2005 Mar;8(3):288-296.
Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.
Simeone A., et al EMBO J. 1992 Jul;11(7):2541-2550.
Otx2
Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.
Ueno M., et al Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9554-9559.
Bf1
Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain.
Tao W., et al Neuron. 1992 May;8(5):957-966.
Directed differentiation of telencephalic precursors from embryonic stem cells.
Watanabe K., et al Nat Neurosci. 2005 Mar;8(3):288-296.
Rx
rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina.
Furukawa T., et al Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3088-3093.
Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.
Ikeda H., et al Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11331-11336.
Irx3
Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system.
Bosse A., et al Mech Dev. 1997 Dec;69(1-2):169-181.
Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification.
Bellefroid E. J., et al EMBO J. 1998 Jan 2;17(1):191-203.
Crx
Complementary homeo protein gradients in developing limb buds.
Oliver G., et al Genes Dev. 1989 May;3(5):641-650.
Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes.
Chen S., et al Neuron. 1997 Nov;19(5):1017-1030.